首页>研究单元>中国科学院合成生物学重点实验室>研究成果>发表文章>2014

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  1. Gu Y*, Jiang Y, Yang S, Jiang WH*. (2014) Utilization of economical substrate-derived carbohydrates by solventogenic clostridia: pathway dissection, regulation and engineering. Curr Opin Biotech. 29: 124-131.
  2. Jiang Y, Liu JL, Yang YL, Jiang WH, Yang S*. (2014) Current status and prospects of industrial bio-production of n-butanol in China. BiotechnologyAdvances. doi.org/10.101610.007.
  3. Yan X, Fan Y, Wei W, Wang PP, Liu QF, Zhang L, Zhao GP*, Yue JM*, Zhou ZH*. (2014) Production of bioactive ginsenoside compound K in metabolically engineered yeast. Cell Res. 24(6): 770-773.
  4. Wang YP, Zhou LS, Zhao YZ, Wang SW, Chen LL, Liu LX, Ling ZQ, Hu FJ, Sun YP, Zhang JY, Yang C, Yang Y, Xiong Y, Guan KL, Ye D. (2014) Regulation of G6PD acetylation by SIRT2 and KAT9 modulates NADPH homeostasis and cell survival during oxidative stress. EMBO J. 33(12): 1304-1320.
  5. Yu LL, Chen HP, Sun JY, Li LG*. (2014) PtrKOR1 is required for secondary cell wall cellulose biosynthesis in Populus. Tree Physiol. 34(11): 1289-300.
  6. Lin W, Wang Y, Han XB, Zhang ZL, Wang CY, Wang J, Yang HY, Lu YH, Jiang WH, Zhao GP*, Zhang P*. (2014) Atypical OmpR/PhoB subfamily response regulator GlnR of actinomycetes functions as a homodimer stabilized by the unphosphorylated conserved Asp-focused charge interactions. J Biol Chem. 289(22): 15413-15425.
  7. Zhang ZL, Wu J, Lin W, Wang J, Yan H, Zhao W, Ma J, Ding JP*, Zhang P*, Zhao GP*. (2014) Subdomain II of α-isopropylmalate synthase is essential for activity: Inferring a mechanism of feedback inhibition. J Biol Chem. 289(40): 27966-27978.
  8. Wang Y, Li C, Duan N, Li B, Ding XM, Yao YF, Hu J*, Zhao GP*, Wang J*. (2014) GlnR negatively regulates the transcription of the alanine dehydrogenase encoding gene ald in Amycolatopsis mediterranei U32 under nitrogen limited conditions via specific binding to its major transcription initiation site. PLoS One. 9(8): e104811.
  9. Liu JK, Chen WH, Ren SX, Zhao GP*, Wang J*. (2014) iBrick: A new standard for iterative assembly of biological parts with homing endonucleases. PLoS One. 9(10): e110852.
  10. Huang LL, Zhu WN, He P, Zhang Y, Zhuang XR, Zhao GP, Guo XK, Qin JH*, Zhu YZ*. (2014) Re-characterization of an extrachromosomal circular plasmid in the pathogenic Leptospira interrogans serovar Lai strain 56601. Acta Biochim Biophys Sin (Shanghai). 46(7): 605-611.
  11. Xu L, Huang H, Wei W, Zhong Y, Tang B, Yuan H, Zhu L, Huang WY, Ge M, Yang S, Zheng HJ, Jiang WH*, Chen DJ*, Zhao GP*, Zhao W*. (2014) Complete genome sequence and comparative genomic analyses of the vancomycin-producing Amycolatopsis orientalis. BMC Genomics. 15: 363.
  12. Zhao LQ, Zhong L, Qin ZJ*. (2014) Two distinct conjugal transfer systems on Streptomyces plasmid pZL1. Acta Biochim Biophys Sin. 46(12): 1084-1086.
  13. Jin L, Zhang H, Chen LW, Yang S, Jiang WH*, Gu Y*. (2014) Combined overexpression of genes involved in pentose phosphate pathway enables enhanced d-xylose utilization by Clostridium acetobutylicum. J Biotechnol. 173: 7-9.
  14. Yu ZY, Zhu H, Zheng GS, Jiang WH*, Lu YH*. (2014) A genome-wide transcriptomic analysis reveals diverse roles of the two-component system DraR-K in the physiological and morphological differentiation of Streptomyces coelicolor. Appl Microbiol Biot. 98: 9351-9363.
  15. Yang JJ, Sun BB, Huang H, Jiang Y, Diao LY, Chen B, Xu CM, Wang X, Liu JL, Jiang WH, Yang S*. (2014) High-efficiency scarless genetic modification in Escherichia coli by using lambda Red recombination and I-SceI cleavage. Appl Environ Microbiol. 80(13): 3826-3834.
  16. Tao RS, Jiang Y, Zhu FY, Yang S. (2014) One-pot L-2-aminobutyric acid production from L-threonine by L-threonine deaminase, L-leucine dehydrogenase and formate dehydrogenase based NADH regeneration system. Biotechnol lett. 36: 835-841.
  17. Gao SL, Han LN, Zhu L, Ge M, Yang S*, Jiang Y*, Chen DJ*. (2014) One-step integration of multiple genes into the oleaginous yeast Yarrowia lipolytica. Biotechnol Lett. 36(12):2523-8.
  18. Chen L, Zou G, Zhang L, Ronald P. de Vries, Yan X, Zhang J, Liu R, Wang CS, Qu YB, Zhou ZH*. (2014) The distinctive regulatory roles of PrtT in the cell metabolism of Penicillium oxalicum. Fungal Genet Biol. 63: 42-54.
  19. Liu T, Zhu L, Wei W, Zhou ZH*. (2014) Function of glucose catabolic pathways in hydrogen production from glucose in Rhodobacter sphaeroides 6016. Int. J. Hydrogen Energy. 39(9): 4215-4221.
  20. Liu D, Yang C*. (2014) The nitrogen-regulated response regulator NrrA controls cyanophycin synthesis and glycogen catabolism in the cyanobacterium Synechocystis sp. PCC 6803. J Biol Chem. 289(4): 2055-71.
  21. Liu DF, Ai GM, Zheng QX, Liu C, Jiang CY, Liu LX, Zhang B, Liu YM, Yang C*, Liu SJ*. (2014) Metabolic flux responses to genetic modification for shikimic acid production by Bacillus subtilis strains. Microb Cell Fact. 13: 40.
  22. Zhang L, Nie XQ, Ravcheev D, Rodionov D, Sheng J, Gu Y, Yang S, Jiang WH, Yang C*. (2014) Redox-Responsive Repressor Rex Modulates Alcohol Production and Oxidative Stress Tolerance in Clostridium acetobutylicum. J. Bacteriol. 196(22): 3949-3963.
  23. Wang JF, Xiong ZQ, Yang YY, Zhao N, Wang Y*. (2014) Significant expression of a Chinese scorpion peptide, BmK1, in Escherichia coli through promoter engineering and gene dosage strategy. Biotechnol Appl Biochem. 61(4):466-473.
  24. Sun ZQ, Meng HL, Li J, Wang JF, Li Q, Wang Y*, Zhang Y*. (2014) Identification of Novel Knockout Targets for Improving Terpenoids Biosynthesis in Saccharomyces cerevisiae. PLoS One. 9(11):e112615.
  25. Zhao YJ, Sun JY, Xu P, Zhang R, Li LG*. (2014) Intron-Mediated Alternative Splicing of PtrWND1B Regulates Cell Wall Thickening during Fiber Development in Populus. Plant Physiol. 164: 765-776.
  26. Song DL, Sun JY, Li LG*. (2014) Diverse roles of PtrDUF579 proteins in Populus and PtrDUF579-1 function in vascular cambium proliferation during secondary growth. Plant Mol Biol. 85(6): 601-12.
  27. Xu P, Kong YM, Song DL, Huang C, Li X, Li LG*. (2014) Conservation and functional influence of alternative splicing in wood formation of Populus and Eucalyptus. BMC Genomics. 15:780.
  28. Wang K, Xiang XH, Qiao N, Qi JY, Lin LB, Zhang R, Shou XJ, Ping XJ, Han JS, Han JD, Zhao GP** & Cailian Cui* (2014) Genomewide analysis of rat periaqueductal gray-dorsalhorn reveals time-, region- and frequency-specific mRNA expression changes inresponse to electroacupuncture stimulation. Sci Rep. 4:6713.
  29. Yin SY, Yang J, Lin B, Deng WJ, Zhang YC, Yi XF, Shi YF, Tao Y, Cai J, Wu CI, Zhao GP, Hurst Laurence D., Zhang J, Hu LD* & Kong XY* (2014) Exome sequencing identifies frequent mutationof MLL2 in non-small cell lung carcinoma from Chinese patients. Sci Rep. 4:6036.
  30. Xiong FF, Xia LL, Wang JF, Wu B, Wang DY, Yuan LF, Cheng YT, Zhu HY, Che XY, Zhang QH, Zhao GP, Wang Y*. (2014) A high-affinity CDR-grafted antibody against influenza A H5N1 viruses recognizes a conserved epitope of H5 hemagglutinin. PLoS One. 9(2): e88777.
  31. Hu ZY, Wang YZ, Im WT, Wang SY, Zhao GP, Zheng HJ*, Quan ZX*. (2014) The first complete genome sequence of the class Fimbriimonadia in the phylum Armatimonadetes. PLoS One. 9(6): e100794.
  32. Zou H, Wang K, Gao Y, Song HG, Xie QL, Jin ML, Zhao GP*, Xiao HS*, and Yu L* (2014) Chronic alcohol consumption from adolescence-to-adulthood in mice - hypothalamic gene expression changes in the dilated cardiomyopathy signaling pathway. BMC Neurosci. 15(1): 61.
  33. Wang K, Song HG, Jin ML, Xiao HS, Zhao GP*, Zou H*, Yu L* (2014) Chronic alcoholconsumption from adolescence to adulthood in mice - Hypothalamic gene expression changes in insulin-signaling pathway. Alcohol. 48(6): 571-578.
  34. Li XL, Chen XF, Hu GH, Liu Y, Zhang ZG, Wang P, Zhou Y, Yi XF, Zhang J, Zhu YF, Wei ZJ, Yuan F, Zhao GP, Zhu J, Hu LD, and Kong XY* (2014) Combined analysis with copy numbervariation identifies risk loci in lung cancer. Biomed Res Int. doi: 10.1155/2014/469103.
  35. Xu L, Li YM, Zhu L, Zhao W, Chen DJ, Huang WY and Yang S*. (2014) Characterization of plasmid pXL100 from Amycolatopsis orientalis HCCB10007 and construction of a shuttle vector. J basic microbiol. 54: 1-8
  36. Sun ZQ, Meng HL, Li J, Wang JF, Li Q, Wang Y*, Zhang Y*. (2014) Identification of Novel Knockout Targets for Improving Terpenoids Biosynthesis in Saccharomyces cerevisiae. PLoS One. 9(11):e112615.
  37. Yu Y, Li X, Hao P, Wang JF* and Chou KC. (2014) Research/Review: structure and linkage disequilibrium analysis of adamantane resistant mutations in influenza virus m2 proton channel. Curr Drug Metab. 15(5): 526-34.
  38. Ma L, Ma Q, Li X, Cheng LL*, Li K* and Li S*. (2014) Transcriptomic analysis of differentially expressed genes in the Ras1(CA)-overexpressed and wildtype posterior silk glands. BMC Genomics. 15:182.
  39. 张明娥, 熊智强, 刘巧霞, 杨迎迎, 王勇* (2014) 一株真菌所产环缩酸肽类化合物的分离和鉴定. 华东理工大学学报(自然科学版). 40(1): 58-64.
  40. 汪建峰, 张嗣良, 王勇* (2014) 大肠杆菌中从头合成白藜芦醇途径的设计及优化. 中国生物工程杂志. 34(2): 71-77.
  41. 汪建峰, 熊智强, 张嗣良, 王勇* (2014) 基于2-C-甲基-D-赤藓糖醇4-磷酸途径的产紫槐二烯大肠杆菌构建及其补糖策略优化. 生物工程学报. 30(1):64-75.
  42. 王鑫(WANG, Xin), 王珂*, 赵国屏* (2014) 疼痛的遗传学研究进展. 中国疼痛医学杂志Chinese Journal of Pain Medicine. 20(7): 500-504.
  43. 欧广云, 熊智强, 周圣靓, 王勇*, 李平 (2014) 阿维链霉菌来源的磷脂酰丝氨酸合成酶基因的克隆及其在毕氏酵母中的异源表达. 工业微生物. 44(1): 28-33.