昆虫适应性进化研究组(詹帅)----中国科学院分子植物科学卓越创新中心/中国科学院上海植物生理生态研究所

昆虫适应性进化研究组(詹帅)

研究组长：詹帅

詹帅，博士，研究员，博士生导师。2010年毕业于中国科学院上海生命科学研究院植物生理生态研究所；2010-2014年在美国马萨诸塞大学医学院（UMASS Medical School）神经生物学系从事博士后研究；2014年3月起在中科院上海植物生理生态研究所任研究员、研究组长。主要从事昆虫适应性进化研究，利用经典遗传学、群体遗传学、基因组学和生物信息等手段，系统研究适应性进化驱动的昆虫种群分化与物种形成、探究昆虫在适应环境过程中复杂行为和复杂性状的形成机制和演化模式。研究成果先后发表在Nature、Cell、Nature Ecology & Evolution、Nature Communications、Cell Research、Molecular Ecology and Biology、The ISME Journal、Nucleic Acids Research、Development等国际学术期刊。入选国家海外高层次人才引进（青年）计划，获基金委优秀青年科学基金项目、中科院前沿科学重点研究项目等资助。

研究方向：

（1）昆虫在种群水平的适应性进化，解析复杂性状（行为）形成的分子机制；

（2）昆虫基因组进化与比较基因组研究，解析大尺度演化格局；

（3）重要昆虫物种的基因组和功能基因组研究。

研究团队：

助理研究员 李贵云

博士后 刘晓静

研究生 潘云洁、林榕梅、房刚奇、崔茜、刘永健、郑诗芮、齐梦梦、张翼翔、王陈润姝

毕业生 刘晓静、卢中文、武宁宁

发表论文：

1. Wu N^#, Zhang S^#, Li X^#, Cao Y, Liu X, Wang Q, Liu Q, Liu H, Hu X, Zhou XJ, James AA, Zhang Z*, Huang Y*, Zhan S*. (2019) Fall webworm geomes yield insights into rapid adaptation of invasive species. Nature Ecology & Evolution 3: 105-115.

2. Xiang H^#, Liu X^#, Li M^#, Zhu Y, Wang L, Cui Y, Liu L, Fang G, Qian H, Xu A*, Wang W*, Zhan S* (2018) The evolutionary road from wild moth to domestic silkworm. Nature Ecology & Evolution 2: 1268-1279.

3. Li S*^#, Zhu S^#, Jia Q^#, Yuan D^#, Ren C^#, Li K, Liu S, Cui Y, Zhao H, Cao Y, Fang G, Li D, Zhao X, Zhang J, Yue Q, Fan Y, Yu X, Feng Q, Zhan S*. (2018) The genomic and functional landscapes of developmental plasticity in the American cockroach. Nature Communications 9: 1008.

4. Zhan S*, Zhang W, Niitepold K, Hsu J, Haeger JF, Zalucki MP, Altizer S, de Roode JC, Reppert SM, Kronforst MR*. (2014) The genetics of monarch butterfly migration and warning colouration. Nature 514:317-321.

5. Zhan S and Reppert SM (2012) MonarchBase: the monarch butterfly genome database. Nucleic Acids Research 41: D758-D763.

6. Zhan S, Merlin C, Boore JL and Reppert SM (2011) The monarch butterfly genome yields insights into long-distance migration. Cell 147: 1171-1185.

7. Zhan S^#, Guo Q^#, Li M, Li M, Li J, Miao X and Huang Y*. (2010) Disruption of an N-acetyltransferase gene in the silkworm reveals a novel role in pigmentation. Development 137: 4083-4090.

8. Zhang S, Shen S, Peng J, Zhou X, Kong X, Ren P, Liu F, Han L*, Zhan S*, Huang Y*, Zhang AB*, Zhang Z* (2020) Chromosome-level genome assembly of an important pine defoliator, Dendrolimus punctatus(Lepidoptera; Lasiocampidae). Molecular Ecology Resources doi: 10.1111/1755-0998.13169.

9. Mei L^#, Chen M^#, Shang Y, Tang G, Ye Tao Y, Zeng L, Huang B, Li Z, Zhan S*, Wang C* (2020) Population genomics and evolution of a fungal pathogen after releasing exotic strains to control insect pests for 20 years. The ISME Journal doi: 10.1038/s41396-020-0620-8.

10. Zhan S*^#, Fang G^#, Cai M^#, Kou Z^#, Xu J, Cao Y, Bai L, Zhang Y, Jiang Y, Luo X, Xu J, Xu X, Zheng L, Yu Z, Yang H, Zhang Z, Wang S, Tomberlin JK*, Zhang J*, Huang Y*. (2020) Genomic landscape and genetic manipulation of the black soldier fly Hermetia illucens, a natural waste recycler. Cell Research 30: 50-60.

11. Zhang T^#, Yuan D^#, Xie J, Lei Y, Li J, Fang G, Tian L, Liu J, Cui Y, Zhang M, Xiao Y, Xu Y, Zhang J, Zhu M, Zhan S*, Li S*. (2019) Evolution of the cholesterol biosynthesis pathway in animals. Molecular Biology and Evolution 36: 2548–2556.

12. Quan Q, Hu X, Pan B, Zeng B, Wu N, Fang G, Cao Y, Chen X, Li X, Huang Y*, Zhan S* (2019) Draft genome of the cotton aphid Aphis gossypii. Insect Biochemistry and Molecular Biology 105: 25-32.

13. Liu A^#, Chen W^#, Huang C, Qian C, Liang Y, Li S*, Zhan S*, Luan Y* (2020) MicroRNA evolution provides new evidence for a close relationship of Diplura to Insecta. Systematic Entomology 45: 365–377.

14. Wang Y^#, Chen X^#, Yang Y, Xu J, Fang G, Niu C, Huang Y, Zhan S* (2018) The Masc gene product controls masculinization in the black cutworm, Agrotis ipsilon. Insect Science 26: 1037-1044.

15. Qiu C^#, Zhang Y^#, Fan Y^#, Pang T, Su Y, Zhan S*, Xu Y* (2018) HITS-CLIP reveals sex-differential RNA binding and alterative splicing regulation of SRm160 in Drosophila. J Mol Cell Biol 11: 170-181.

16. Xu J, Xu X, Zhan S, Huang Y (2019) Genome editing in insects: current status and challenges. National Science Review 6: 399-401.

17. Chen C, Liu Y, Song W, Chen D, Chen F, Chen X, Chen Z, Ge S, Wang C, Zhan S, Chen X, Mao Y* (2019) An effector from cotton bollworm oral secretion impairs host plant defense signaling. PNAS 116: 14331-14338.

18. Shang Y, Xiao G, Zheng P, Cen K, Zhan S, Wang C. (2016) Divergent and Convergent Evolution of Fungal Pathogenicity. Genome Biology and Evolution 8: 1374-87.

19. Zeng B, Zhan S, Wang Y, Huang Y, Xu J, Liu Q, Li Z, Huang Y, Tan A. (2016) Expansion of CRISPR targeting sites in Bombyx mori. Insect Biochemistry and Molecular Biology 72: 31-40.

20. Gao JL, Fan YJ, Wang XY, Zhang Y, Pu J, Li L, Shao W, Zhan S, Hao J, Xu YZ. (2015) A conserved intronic U1 snRNP-binding sequence promotes trans-splicing in Drosophila. Genes & Development 29: 760-71.

21. Hu X, Xiao G, Zheng P, Shang Y, Su Y, Zhang X, Liu X, Zhan S, St Leger RJ, Wang C. (2015) Trajectory and genomic determinants of fungal-pathogen speciation and host adaptation. PNAS 111: 16796-801.

22. Zhan S^#, Huang J^#, Guo Q., Zhao Y., Li W., Miao X., Goldsmith MR, Li M* and Huang Y*. (2009) An integrated genetic linkage map for silkworms with three parental combinations and its application to the mapping of single genes and QTL. BMC Genomics 10: 389.