首页>研究单元>中国科学院合成生物学重点实验室>研究成果>发表文章>2013

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  1. Weihua Chen, Zhongjun Qin, Jin Wang*, Guoping Zhao* (2013) The MASTER (methylation-assisted tailorable ends rational) ligation method for seamless DNA assembly. Nucleic Acids Res. 41(8): e93.
  2. Liangdong Lyu*, Bikui Tang, Xiaoyong Fan, Hui Ma, Guoping Zhao* (2013) Mycobacterial mazG safeguards genetic stability via housecleaning of 5-OH-dCTP. PLoS Pathog. 9(12): e1003814.
  3. Ying Wang, Jingzhi Wang, Zhihui Shao, Hua Yuan, Yinhua Lu, Weihong Jiang, Guoping Zhao*, Jin Wang* (2013) Three out of four GlnR binding sites are essential for GlnR-mediated activation of the transcription of Amycolatopsis mediterranei nas operon. J Bacteriol. 195(11): 2595-2602.
  4. Yunyi Zhang, Ke Dong, Lingbing Zeng, Qingtian Li, Chang Liu, Jin Wang, Xiaokui Guo*, Guoping Zhao* (2013) Genetic and molecular biological characterization of two homologous cheR genes from Leptospira interrogans. Acta Bioch Bioph Sin. 45(10): 806-816.
  5. Xiaodong Shang, Qi Tan, Ruina Liu, Kangying Yu, Pingzuo Li, Guoping Zhao (2013) In Vitro Anti-Helicobacter pylori Effects of Medicinal Mushroom Extracts, with Special Emphasis on the Lion's Mane Mushroom, Hericium erinaceus (Higher Basidiomycetes). Int J Med Mushrooms. 15(2): 165-174.
  6. Lin Zhang, Binyan Zhu, Ruixue Dai, Guoping Zhao*, Xiaoming Ding* (2013) Control of directionality in Streptomyces phage φBT1 integrase-mediated site-specific recombination. PLoS One. 8(11): e80434.
  7. Bo Zhang, Lin Zhang, Ruixue Dai, Yu Meiying, Guoping Zhao*, Xiaoming Ding* (2013) An Efficient Procedure for Marker-Free Mutagenesis of S. coelicolor by Site-Specific Recombination for Secondary Metabolite Overproduction. PLoS One. 8(2): e55906.
  8. Guodong Liu, Lei Zhang, Yuqi Qin, Gen Zou, Zhonghai Li, Xing Yan, Xiaomin Wei, Mei Chen, Ling Chen, Kai Zheng, Jun Zhang, Liang Ma, Jie Li, Rui Liu, Hai Xu, Xiaoming Bao, Xu Fang, Lushan Wang, Yaohua Zhong, Weifeng Liu, Huajun Zheng, Shengyue Wang, Chengshu Wang, Luying Xun, Guoping Zhao*, Tianhong Wang*, Zhihua Zhou*, Yinbo Qu* (2013) Long-term strain improvements accumulate mutations in regulatory elements responsible for hyper-production of cellulolytic enzymes. Sci Rep. 3: 1569.
  9. Biao Tang, Qi Wang, Minjun Yang, Feng Xie, Yongqiang Zhu, Ying Zhuo, Shengyue Wang, Hong Gao, Xiaoming Ding, Lixin Zhang*, Guoping Zhao*, Huajun Zheng* (2013) ContigScape: a Cytoscape plugin facilitating microbial genome gap closing. BMC Genomics. 14(1): 289.
  10. Wen Zhang, Yuanyuan Zhang, Huajun Zheng, Yuanlong Pan, Haican Liu, Pengcheng Du, Li Wan, Jun Liu, Baoli Zhu*, Guoping Zhao*, Chen Chen*, Kanglin Wan* (2013) Genome Sequencing and Analysis of BCG Vaccine Strains. PLoS One. 8(8): e71243.
  11. Changming Cheng*, Jie Wang, Chao Yang, Yin Zhou, Juan Chen, Jie Zhang, Nengqin Jia*, Hongmei Cao, Guoping Zhao (2013) Electrochemiluminescent assay for detection of extremely rare mutations based on ligase reaction and bead enrichment. Anal Biochem. 434(1): 34-38.
  12. Chunsheng Dong*, Guoping Zhao, Mei Zhong, Yan Yue, Li Wu, Sidong Xiong* (2013) RNA sequencing and transcriptomal analysis of human monocyte to macrophage differentiation. Gene. 519(2): 279-287.
  13. Changming Cheng*, Yin Zhou, Chao Yang, Juan Chen, Jie Wang, Jie Zhang, Guoping Zhao (2013) Detection of rare point mutation via allele-specific amplification in emulsion PCR. BMB Rep. 46(5): 270-275.
  14. Di Liu, Weifeng Shi, Yi Shi, Dayan Wang, Haixia Xiao, Wei Li, Yuhai Bi, Ying Wu, Xianbin Li, Jinghua Yan, Wenjun Liu, Guoping Zhao, Weizhong Yang, Yu Wang, Juncai Ma, Yuelong Shu*, Fumin Lei*, George F Gao* (2013) Origin and diversity of novel avian influenza A H7N9 viruses causing human infection: phylogenetic, structural, and coalescent analyses. Lancet. 381(9881): 1926-1932.
  15. Huajun Zheng, Wenbao Zhang*, Liang Zhang, Zhuangzhi Zhang, Jun Li, Gang Lu, Yongqiang Zhu, Yuezhu Wang, Yin Huang, Jing Liu, Hui Kang, Jie Chen, Lijun Wang, Aojun Chen, Shuting Yu, Zhengchao Gao, Lei Jin, Wenyi Gu, Zhiqin Wang, Li Zhao, Baoxin Shi, Hao Wen, Renyong Lin, Malcolm K Jones, Brona Brejova, Tomas Vinar, Guoping Zhao, Donald P McManus*, Zhu Chen*, Yan Zhou*, Shengyue Wang* (2013) The genome of the hydatid tapeworm Echinococcus granulosus. Nat Genet. 45(10): 1168-1175.
  16. Dapeng Bao*, Ming Gong, Huajun Zheng, Mingjie Chen, Liang Zhang, Hong Wang, Jianping Jiang, Lin Wu, Yongqiang Zhu, Gang Zhu, Yan Zhou, Chuanhua Li, Shengyue Wang, Yan Zhao, Guoping Zhao, Qi Tan* (2013) Sequencing and Comparative Analysis of the Straw Mushroom (Volvariella volvacea) Genome. PLoS One. 8(3): e58294.
  17. Yi Jiang, Hai-can Liu, Huajun Zheng, Xiangfeng Dou, Biao Tang, Xiu-qin Zhao, Yongqiang Zhu, Bing Lu, Shengyue Wang, Hai-yan Dong, Yuan-yuan Zhang, Guoping Zhao, Kanglin Wan* (2013) 19-VNTR loci used in genotyping Chinese clinical Mycobacterium tuberculosis complex strains and in association with spoligotyping. J Basic Microbiol. 53(7): 562-580.
  18. Chenhong Zhang, Shoufeng Li, Liu Yang, Ping Huang, Wenjun Li, Shengyue Wang, Guoping Zhao, Menghui Zhang, Xiaoyan Pang, Zhen Yan, Yong Liu*, Liping Zhao* (2013) Structural modulation of gut microbiota in life-long calorie-restricted mice. Nat Commun. 4: 2163.
  19. Yong Zhang, Weiyi Ye, Jiaqi Wang, Shujun Wang, Ping Ji, Guangyan Zhou, Guoping Zhao, Hailiang Ge, Ying Wang* (2013) dCTP pyrophosphohydrase exhibits nucleic accumulation in multiple carcinomas. Eur J Histochem. 57(3): e29.
  20. Rui Wang, Yvonne Mast, Jin Wang, Weiwen Zhang, Guoping Zhao, Wolfgang Wohlleben, Yinhua Lu*, Weihong Jiang* (2013) Identification of two-component system AfsQ1/Q2 regulon and its cross-regulation with GlnR in Streptomyces coelicolor. Mol Microbiol. 87(1):30-48.
  21. Yunliang Chen**, Hong Zhu**, Guosong Zheng, Weihong Jiang, Yinhua Lu* (2013) Functional analysis of TetR-family regulator AmtRsav in Streptomyces avermitilis. Microbiology. 159: 2571–2583.
  22. Liuyang Diao, Yingmiao Liu, Fenghui Qian, Junjie Yang, Yu Jiang, Sheng Yang* (2013) Construction of fast xylose-fermenting yeast based on industrial ethanol-producing diploid Saccharomyces cerevisiae by rational design and adaptive evolution. BMC Biotechnol. 13(1):110.
  23. Zhilin Li, Han Xiao, Weihong Jiang, Yu Jiang*, Sheng Yang* (2013) Improvement of solvent production from xylose mother liquor by engineering the xylose metabolic pathway in Clostridium acetobutylicum EA 2018. Appl Biochem Biotech. 171(3):555-68.
  24. Kuan Hu, Meng Zhao, Tianlong Zhang, Manwu Zha, Chen Zhong, Yu Jiang* and Jianping Ding* (2013) Structures of trans-2-enoyl-CoA reductases from Clostridium acetobutylicum and Treponema denticola: insights into the substrate specificity and the catalytic mechanism. Biochem J. 449(1):79-89.
  25. Shiyuan Peng, Ana Zeng, Li Zhong, Ran Zhang, Min Zhou, Qiuxiang Cheng, Liqian Zhao, Tao Wang, Huarong Tan, Zhongjun Qin* (2013) Three functional replication origins of the linear and artificially-circularized plasmid SCP1 of Streptomyces coelicolor. Microbiology. 159: 2127-2140.
  26. Yalan Chen, Huarong Tan, Zhongjun Qin* (2013) Characterization of a replication locus and formation of a higher-order complex between RepA protein and two inverted-repeats in Streptomyces plasmid pSV1. FEMS Microbiol Lett. 349(2): 144-152.
  27. Ran Zhang, Haiyang Xia, Qingyu Xu, Fujun Dang, Zhongjun Qin* (2013) Recombinational cloning of the antibiotic biosynthetic gene clusters in linear plasmid SCP1 of Streptomyces coelicolor A3(2). FEMS Microbiol Lett. 345(1): 39-48.
  28. Pengfei Xie, Ana Zeng, Zhongjun Qin* (2013) A putative transglycosylase encoded by SCO4132 influences morphological differentiation and actinorhodin production in Streptomyces coelicolor. Act Bioch Bioph Sin. 45(4):296-302.
  29. Yosi Nindita, Tomoya Nishikawa, Kenji Arakawa, Guojun Wang, Kozo Ochi, Zhongjun Qin and Haruyasu Kinashi. (2013) Chromosomal circularization of the model Streptomyces species, Streptomyces coelicolor A3(2). FEMS Microbiol Lett. 347: 149–155.
  30. Shu Shaohua, Chen Bei, Zhou Mengchun, Zhao Xinmei, Xia Haiyang*, Wang Mo* (2013) De novo sequencing and transcriptome analysis of Wolfiporia cocos to reveal genes related to biosynthesis of triterpenoids. PLoS One. 8(8):e71350.
  31. Xing Yan, Alei Geng, Jun Zhang, Yongjun Wei, Lei Zhang, Changli Qian, Qianfu Wang, Shengyue Wang, Zhihua Zhou* (2013) Discovery of (hemi-) cellulase genes in a metagenomic library from a biogas digester using 454 pyrosequencing. Appl Microbiol Biotech. 97:8173-8182.
  32. Wei Wei, Ling Chen, Gen Zou, Qianfu Wang, Xing Yan, Jun Zhang, Chengshu Wang*, Zhihua Zhou* (2013) N-Glycosylation affects the proper folding, enzymatic characteristics and production of a fungal β-glucosidase. Biotechnol Bioeng. 110 (12): 3075-3084.
  33. Ruisong Yu, Ruofan Wang, Ting Bi, Weining Sun, Zhihua Zhou* (2013) Blocking the butyrate-formation pathway impairs hydrogen production in Clostridium perfringens. Acta Bioch Bioph Sin. 45(5):408-415.
  34. Guodong Liu, Lei Zhang, Xiaomin Wei, Gen Zou, Yuqi Qin, Liang Ma, Jie Li, Huajun Zheng, Shengyue Wang, Chengshu Wang, Luying Xun, Guoping Zhao, Zhihua Zhou*, Yinbo Qu* (2013) Genomic and secretomic analyses reveal unique features of the lignocellulolytic enzyme system of Penicillium decumbens. PLoS One. 8(2): e55185.
  35. Ning Liu, Lei Zhang, Haokui Zhou, Meiling Zhang, Xing Yan, Qian Wang, Yanhua Long, Lei Xie, Shengyue Wang, Yongping Huang, Zhihua Zhou* (2013) Metagenomic insights into metabolic capacities of the gut microbiota in a fungus-cultivating termite. PLoS One. 8(7):e69184.
  36. Qian Han, Ning Liu, Howard Robinson, Lin Cao, Changli Qian, Qianfu Wang, Lei Xie, Haizhen Ding, Qian Wang,Yongping Huang, Jianyong Li*, Zhihua Zhou* (2013) Biochemical characterization and crystal structure of a GH10 xylanase from termite gut bacteria reveal a novel structural feature and significance of its bacterial Ig-like domain. Biotechnol Bioeng. 110 (12): 3093-3103.
  37. Zhiqiang Xiong, Yuyou Hao, Yong Wang* (2013) Recent advances in the discovery and development of marine microbial natural products. Mar Drugs. 11: 700-717.
  38. Hailin Meng, Jiagfeng Wang, Zhiqiang Xiong,, Feng Xu, Guoping Zhao, Yong Wang* (2013) Quantitative design of regulatory elements based on high-precision strength prediction using artificial neural network. PLoS One 8(4): e60288.
  39. Jianfeng Wang, Zhiqiang Xiong, Shiyuan Li, Yong Wang* (2013) Enhancing isoprenoid production through systematically assembling and modulating efflux pumps in Escherichia coli. Appl Microbiol Biotechnol. 97: 8057-8067.
  40. Zhiqiang Xiong, Yingying Yang, Na Zhao, Yong Wang* (2013) Diversity of endophytic fungi and screening of fungal paclitaxel producer from Anglojap yew, Taxus x media. BMC Microbiol. 13: 71.
  41. Bohu Pan, Jia Sheng, Weining Sun, Yinhong Zhao, Pei Hao*, Xuan Li* (2013) OrysPSSP: a comparative platform for small secreted proteins from rice and other plants. Nucleic Acids Res. 41(D1):D1192-8.
  42. Zhijian Cao, Yao Yu, Yingliang Wu, Pei Hao, Zhiyong Di, Yawen He, Zongyun Chen, Weishan Yang, Zhiyong Shen, Xiaohua He, Jia Sheng, Xiaobo Xu, Bohu Pan, Jing Feng, Xiaojuan Yang, Wei Hong, Wenjuan Zhao, Zhongjie Li, Kai Huang, Tian Li, Yimeng Kong, Hui Liu, Dahe Jiang, Binyan Zhang, Jun Hu, Youtian Hu, Bin Wang, Jianliang Dai, Bifeng Yuan, Yuqi Feng, Wei Huang, Xiaojing Xing, Guoping Zhao, Xuan Li*, Yixue Li*, Wenxin Li* (2013) The genome of Mesobuthus martensii reveals a unique adaptation model of arthropods. Nat Commun. 4: 2602.
  43. Xinchao Wang, Qiongyi Zhao , Chunlei Ma, Zonghong Zhang, Hongli Cao, Yimeng Kong, Chuan Yue, Xinyuan Hao, Liang Chen, Jian-Qiang Ma1, Jiqiang Jin, Xuan Li*, Yajun Yang*.(2013) Global transcriptome profiles of Camellia sinensis during cold acclimation. BMC Genomics. 14(1):415.
  44. Liangxiao Ma, Yajun Wang, Jingfang Wang, Xuan Li, and Pei Hao* (2013) Expression snsitivity analysis of human disease related genes. BioMed Res Int. 2013:637424.
  45. Shuhao Yu, Lulu Zheng, Yixue Li, Chunyan Li, Chenchen Ma, Yang Yu, Xuan Li, Pei Hao*. (2013) Causal co-expression method with module analysis to screen drugs with specific target. Gene. 518(1):145-51.
  46. Yue Liu, Bingya Liu, Pei Hao*, Xuan Li, Yixue Li, Jingfang Wang*. (2013) π-π stacking mediated drug-drug interactions in human CYP2E1. Proteins. 81(6):945-54.
  47. Chenchen Liu,Liang Xiao, Jianxiong Jiang, Wangxia Wang, Feng Gu, Dongliang Song, Zili Yi, Yongcan Jin, Laigeng Li* (2013) Biomass properties from different Miscanthusspecies. Food Energy Secur. 2(1):12-19.
  48. Yunjun Zhao, Dongliang Song, Jiayan Sun, Laigeng Li* (2013) Populus endo-beta-mannanase PtrMAN6 plays a role in coordinating cell wall remodeling with suppression of secondary wall thickening through generation of oligosaccharide signals. Plant J. 4:473-485.
  49. Yingying Zhu, Dongliang Song, Jiayan Sun, Wang Xi, Laigeng Li* (2013) PtrHB7, a class III HD-Zip gene, plays a critical role in regulation of vascular cambium differentiation in Populus. Mol Plant. 6(4):1331-1343.
  50. LiangliangYu, Jiayan Sun, Laigeng Li* (2013) PtrCel9A6, an endo-1,4-β-glucanase, is required for cell wall formation during xylem differentiation in Populus. Mol Plant. 6(6):1904-1917.
  51. Peng Xu, Yimen Kong, Xuan Li, LaigengLi* (2013) Identification of molecular processes needed for vascular formation through transcriptome analysis of different vascular systems. BMC Genomics. 14: 217.
  52. Yunjun Zhao, Qian Zhang, Luxia Yuan, Rui Zhang, Laigeng Li* (2013) N-glycosylation and dimerization regulate the PtrMAN6 enzyme activity that may modulate generation of oligosaccharide signals. Plant Signal Behav. 8:e26956.
  53. Jia Xu, Xiaoguang Duan, Jun Yang, John Reader Beeching, Peng Zhang* (2013) Enhanced reactive oxygen species scavenging by overproduction of superoxide dismutase and catalase delays post-harvest physiological deterioration of cassava storage roots. Plant Physiol. 161(3): 1517-1528.
  54. Hongxia Wang, Weijuan Fan, Hong Li, Jun Yang, Jirong Huang, Peng Zhang* (2013) Functional characterization of dihydroflavonol-4-reductase in anthocyanin biosynthesis of purple sweet potato underlies the direct evidence of anthocyanins function against abiotic stresses. PLoS ONE, 8(11): e78484.
  55. Xiaoguang Duan, Jia Xu, Erjun Ling, Peng Zhang* (2013) Expression of Cry1Aa in cassava improves its insect resistance against Helicoverpa armigera. Plant Mol Biol. 83(1-2):131-141.
  56. Jia Xu, Xiaoguang Duan,Jun Yang, John Reader Beeching, Peng Zhang* (2013) Coupled expression of Cu/Zn-superoxide dismutase and catalase in cassava improves tolerance against cold and drought stresses. Plant Signal Behav. 8: e24525.
  57. Jihong Liu Clarke, Peng Zhang (2013) Plant biotechnology for food security and bioeconomy. Plant Mol Biol. 83:1-3.
  58. Agnès Rolland-Sabaté*, Teresa Sanchez, Alain Buléon, Paul Colonna, Hernan Ceballos, Shan-Shan Zhao, Peng Zhang, Dominique Dufour (2013) Molecular and supra-molecular structure of waxy starches developed from cassava (Manihot esculenta Crantz). Carbohyd Polym. 92(2): 1451-1462.
  59. Feng Sun, Chao Liang, James Whelan, Jun Yang, Peng Zhang and Boon Leong Lim (2013) Global transcriptome analysis of AtPAP2 -overexpressing Arabidopsisthaliana with elevated ATP. BMC Genomics. 14:752.
  60. Jia Xu, John K. Fellman, Peng Zhang* (2013) Fluorescence Measurement of Postharvest Physiological Deterioration (PPD) in Cassava Storage Roots. WWW.BIO-PROTOCOL.ORG (Featured protocol).
  61. Sowmya Viswanathan, Pingzuo Li, Wonbong Choi, Slawomir Filipek, T. A. Balasubramaniam,k and V. Renugopalakrishnan (2012) Protein–Carbon Nanotube Sensors: Single Platform Integrated Micro Clinical Lab for Monitoring Blood Analytes. Methods in Enzymology. 509: 165-194.
  62. Lishan Zhao*, Wei-chen Chang*, Youli Xiao*, Hung-wen Liu*, and Pinghua Liu* (2013) Phosphate Pathway of Isoprenoid Biosynthesis. Annu Rev Biochem. 82: 497-530.
  63. Anjiang Tan, Guoliang Fu, Li Jin, Qiuhong Guo, Zhiqian Li, Baolong Niu, Zhiqi Meng, Neil I. Morrison, Luke Alphey*, and Yongping Huang* (2013) Transgene-based, female-specific lethality system for genetic sexing of the silkworm, Bombyx mori. PNAS. 110(17): 6766–6770.
  64. XinGuang Zhu*, Yu Wang, Donald R. Ort, Stephen P. Long (2013) e-photosynthesis: a comprehensive dynamic mechanistic model of C3 photosynthesis: from light capture to sucrose synthesis. Plant Cell Environ. 36(9):1711-27.
  65. 王世东，赵国屏，张庆华* (2013) 系统生物学在中医“证”本质研究中的应用. 中国中西医结合杂志. 33(1): 131-134.
  66. 林帅帅，白云，李本尚，张璐，马丰收，朱永强，康慧，赵国屏，王升跃* (2013) 儿童急性淋巴细胞性白血病复发期miRNA的表达特征研究. 复旦学报(自然科学版) 52(4): 460-471+569.
  67. 王晶慧, 吴标, 黄玲, 王登宇, 王树军, 王佳琦, 赵琳, 张勇, 沈浩, 赵国屏, 许洁, 王颖* (2013) 不同临床阶段乙型肝炎患者外周CD8+T 淋巴细胞免疫记忆应答水平的比较. 肝脏. 18(6):369-373.
  68. 顾阳，杨晟*，姜卫红* (2013) 产溶剂梭菌分子遗传操作技术研究进展. 生物工程学报. 29(8): 1133？1145.
  69. 李雷，芦银华*，姜卫红* (2013) DNA组装新方法的研究进展. 生物工程学报. 29(8): 1113？1122.
  70. 芦银华，姜卫红 (2013) 链霉菌次级代谢调控相关的双组分系统研究进展. 微生物学通报. (10): 1847-1859.
  71. 覃重军* (2013) 链霉菌质粒的复制与进化. 微生物学通报. 40(10): 1822-1830.
  72. 薛小莉*，覃重军 (2013) 大肠杆菌最小基因组分析和删减进展. 生命科学. 25(10)：978-982.
  73. 汪建峰, 蒙海林, 熊智强, 王勇* (2013) 基于合成生物学的微生物制造研究进展. 生物产业技术. 12-23.
  74. 汪建峰, 蒙海林, 熊智强, 王勇* (2013) 复杂天然产物合成人工生物系统的设计与构建. 生物工程学报. 29(8): 1146-1160.
  75. 杨迎迎, 熊智强, 王勇* (2013) 3种药用植物内生真菌的多样性分析及产生物碱菌株的筛选. 中国抗生素杂志. 38(12): 901-908.
  76. 朱莹莹, 于亮亮, 汪杏芬, 李来庚* (2013) HD-Zip III转录因子家族与植物细胞分化. 植物学报. 48 (2): 199–209.
  77. 张鹏*，安冬，马秋香，王红霞，王连军，许佳，杨俊，周文智 (2013) 木薯分子育种中若干基本科学问题的思考与研究进展. 中国科学：生命科学. 43(12):1082~1089.
  78. 赵姗姗，杨俊，周文智，张鹏* (2013) 薯类植物中的淀粉生物合成及关键酶. 植物学研究 2(1): 24-33.
  79. 凡建刚，褚仲梅，张毅* (2013) Pyrococcus furiosus耐热淀粉酶工程菌的构建及直链麦芽寡糖的制备. 工业微生物. 43(4):34-37.