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Evangelos Tatsis,Principal Investigator、博士生导师

Plant Natural Products Biosynthesis

Website:
Email: etatsis@sippe.ac.cn

个人简介:
Work experience
September 2017 – present: Principle Invistigator Institute of Plant Physiology & Ecology, Shanghai Institutes for Biological Sciences, CAS

October 2013 – August 2017: Senior Post Doc Research Associate in Department of Biological Chemistry, The John Innes Centre, Norwich, UK
Post Doc Advisor: Prof. Sarah O´Connor

April 2008 – September 2013: Post Doc Research Fellow in NMR/Biosynthesis Group, Max Planck Institute for Chemical Ecology, Jena, Germany
Post Doc Advisor: P.D. Dr Bernd Schneider

Education
December 2001 – January 2006: PhD in Chemistry at Department of Chemistry, University of Ioannina, Ioannina, Greece
Thesis Title: Analysis and study of composition of Hypericum perforatum extracts with the use of spectroscopic methods and hyphenated techniques
PhD Advisor: Prof Ioannis P Gerothanassis

October 1996 – January 2001 Bachelor in Chemistry at Department of Chemistry, University of Ioannina, Ioannina, Greece

主要论文:

2017
Evangelos C. Tatsis, Marta Ines Soares Teto Carqueijeiro, Thomas Dugé de Bernonville, Jakob Franke, Thu-Thuy T. Dang, Audrey Oudin, Arnaud Lanoue, Florent Lafontaine, Anna K. Stavrinides, Marc Clastre, Vincent Courdavault, Sarah E. O’Connor. A three enzyme system to generate the Strychnos alkaloid scaffold from a central biosynthetic intermediate. Nature Communications – in press -

Richard M. E. Payne, Deyang Xu, Emilien Foureau, Marta Ines Soares Teto Carqueijeiro, Audrey Oudin, Thomas Dugé de Bernonville, Vlastimil Novak, Meike Burow, Carl-Erik Olsen, D. Marc Jones, Evangelos C. Tatsis, Ali Pendle, Barbara Ann Halkier, Fernando Geu-Flores, Vincent Courdavault, Hussam Hassan Nour-Eldin & Sarah E. O'Connor. An NPF transporter exports a central monoterpene indole alkaloid intermediate from the vacuole. Nature Plants 3: 16208.

2016
Anna Stavrinides, Evangelos C. Tatsis, Lorenzo Caputi, Emilien Foureau, Clare E. M. Stevenson, David M. Lawson, Vincent Courdavault & Sarah E. O'Connor. Structural investigation of heteroyohimbine alkaloid synthesis reveals active site elements that control stereoselectivity. Nature Communications 7: 12116.

Evangelos C. Tatsis & Sarah E. O'Connor. New Development in Engineering Plant pathways. Current Opinion in Biotechnology 42: 126-132.

Anne-Christin Warskulat, Evangelos C. Tatsis, Bettina Dudek, Marco Kai, Sybille Lorenz, Bernd Schneider. An unprecedented utilization of pelargonidin and indole for the biosynthesis of plant indole alkaloids. CHEMBIOCHEM 17(4): 318-327.

2015
Anna Stavrinides, Evangelos C. Tatsis, Emilien Foureau, Lorenzo Caputi, Franziska Kellner, Vincent Courdavault, Sarah E. O’Connor. Unlocking the Diversity of Alkaloids in Catharanthus roseus: Nuclear Localization Suggests Metabolic Channeling in Secondary Metabolism. Chemistry & Biology 22(3): 336–341.

2014
Evangelos C. Tatsis, Eva Eylert, Ravi Kumar Maddula, Elena Ostrozhenkova, Aleš Svatoš, Wolfgang Eisenreich, Bernd Schneider. Biosynthesis of Nudicaulins: A 13CO2-Pulse/Chase Labeling Study with Papaver nudicaule. CHEMBIOCHEM 15(11): 1645-1650.

2013
Evangelos C. Tatsis, Hartmut Böhm, Bernd Schneider. Occurrence and structure of nudicaulins in flowers of papaveraceous species Phytochemistry 92(1): 105-112.

2012
Evangelos C. Tatsis, Anu Schaumlöffel, Anne C. Warskulat, Georges Massiot, Bernd Schneider, Gerhard Bringmann. Nudicaulins, the Elusive Flower Pigments of Yellow Papaver nudicaule – Revised Structure and Absolute Configuration Organic Letters 15(1): 156-159.

Jingjing Fang, Aina Ramsay, Christian Paetz, Evangelos C. Tatsis, Sullivan Renouard, Christophe Hano, Eric Grand, Ophélie Fliniaux, Albrecht Roscher, Francois Mesnard, Bernd Schneider. Concentration kinetics of secoisolariciresinol diglucoside and its biosynthetic precursor coniferin in developing flaxseeds Phytochemical Analysis 224: 41–46.

2008
Evangelos C. Tatsis, Vassiliki Exarchou, Anastassios N. Troganis, Ioannis P. Gerothanassis. 1H-NMR determination of hypericin and pseudohypericin in complex natural mixtures by the use of strongly deshielded OH groups. Analytica Chimica Acta 607(2): 219-226.

2007
Evangelos C. Tatsis, Sjef Boeren, Vassiliki Exarchou, Anastassios N. Troganis, Jacques Vervoort, Ioannis P. Gerothanassis. Identification of the major constituents of Hypericum perforatum by LC/SPE/NMR and/or LC/MS. Phytochemistry 68: 383–393.

2002
Dimitris Skalkos, Evangelos Tatsis, Ioannis P. Gerothanassisb, and Anastasios Troganis. Towards a consensus structure of hypericin in solution: direct evidence for a single tautomer and different ionization states in protic and nonprotic solvents by the use of variable temperature gradient 1H-NMR. Tetrahedron 58(24): 4925-4929.

 
 
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